Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23871973 | 0.80 | TP53 (0.43) | NPC1RAB9ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10252407 | 0.76 | HDAC3 (0.50) | NPC1MITFRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12841585 | 0.76 | HDAC1 (0.47) | KDM4EEGFR | |
| SCHEMBL18726609 | 0.76 | GAA (0.34) | NPC1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL5960697 | 0.76 | SMN1; SMN2 (0.34) | RAB9AALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL20867336 | 0.75 | HDAC1 (0.36) | L3MBTL1LMNAKDM4EEGFR | |
| SCHEMBL10140100 | 0.73 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20861736 | 0.73 | HDAC1 (0.35) | ALDH1A1KDM4EEGFRMEN1KMT2A | |
| SCHEMBL23735849 | 0.72 | — | — | |
| SCHEMBL20082202 | 0.69 | PTPN1 (0.44) | NPC1RAB9ASMN1; SMN2PRMT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |