SCHEMBL22019080

SCHEMBL22019080

Clc1nc(-c2ccccc2)nc(-c2cccc3c4c5ccccc5ccc4n(-c4ccccc4)c23)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
POLB P06746 2/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 2/20 0.36
TSHR P16473 2/20 0.36
TP53 P04637 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
ATM Q13315 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
ABCG2 Q9UNQ0 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21795005 0.86 KDM4E (0.46) KDM4EPOLBCTDSP1TSHRATM
SCHEMBL21863080 0.85 MAPT (0.39) KDM4ESMN1; SMN2MAPTTSHRTP53
SCHEMBL24210569 0.84 KDM4E (0.40) KDM4EPOLBCTDSP1SMN1; SMN2MAPT
SCHEMBL30853444 0.84 KDM4E (0.49) KDM4EPOLBCTDSP1SMN1; SMN2MAPT
SCHEMBL21190680 0.84 KDM4E (0.49) KDM4EPOLBCTDSP1SMN1; SMN2MAPT
SCHEMBL23802635 0.82 KDM4E (0.39) KDM4EPOLBCTDSP1SMN1; SMN2MAPT
SCHEMBL24992304 0.82 KDM4E (0.38) KDM4EPOLBCTDSP1SMN1; SMN2MAPT
SCHEMBL31398838 0.82 KDM4E (0.39) KDM4EPOLBCTDSP1SMN1; SMN2MAPT
SCHEMBL12691001 0.82 RAB9A (0.35) KDM4ESMN1; SMN2MAPTTSHRTP53
SCHEMBL18126014 0.82 KDM4E (0.44) KDM4EPOLBCTDSP1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220020932-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-01-20 US disclosed
WO-2020101169-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020932-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, OR51E2, OR10J3 KDM4E 636/4885POLB 2368/4885CTDSP1 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.