SCHEMBL18126014

SCHEMBL18126014

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c5c6c7ccccc7n(-c7ccccc7)c6ccc5n(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
ATM Q13315 2/20 0.44
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
TSHR P16473 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ALOX15 P16050 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
ADORA1 P30542 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 2/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24164153 0.93 KDM4E (0.43) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL24800687 0.90 KDM4E (0.40) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL17252620 0.89 L3MBTL1 (0.49) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL22879946 0.88 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL20251505 0.88 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL23602244 0.88 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL20251510 0.88 KDM4E (0.38) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL21190489 0.88 L3MBTL1 (0.47) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL23039454 0.88 KDM4E (0.43) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL20251836 0.88 KDM4E (0.38) KDM4EL3MBTL1ATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230292608-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-09-14 US disclosed
US-20230292608-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-09-14 US disclosed
US-11672175-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-06 US disclosed
US-11672175-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-06 US disclosed
US-20200266363-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-20 US disclosed
US-10693082-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-23 US disclosed
US-20160293856-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed
US-20160293856-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160293856-A1 Organic Electroluminescent Materials and Devices ICMT, INMT, PNMT KDM4E 2262/4885L3MBTL1 1157/4885ATM 1749/4885
US-20200266363-A1 Organic Electroluminescent Materials and Devices ICMT, INMT, PNMT KDM4E 2262/4885L3MBTL1 1157/4885ATM 1749/4885
US-11672175-B2 Organic electroluminescent materials and devices ICMT, INMT, PNMT KDM4E 2262/4885L3MBTL1 1157/4885ATM 1749/4885
US-20230292608-A1 Organic Electroluminescent Materials and Devices ICMT, INMT, PNMT KDM4E 2262/4885L3MBTL1 1157/4885ATM 1749/4885
US-10693082-B2 Organic electroluminescent materials and devices ICMT, INMT, PNMT KDM4E 2262/4885L3MBTL1 1157/4885ATM 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.