SCHEMBL22019088

SCHEMBL22019088

Oc1ccc(Cl)cc1-c1cc2ccccc2c2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.57
CDK9 P50750 1/20 0.43
HSP90AA1 P07900 2/20 0.42
HSP90AB1 P08238 2/20 0.42
IDO1 P14902 2/20 0.41
NQO2 P16083 1/20 0.41
PIM1 P11309 1/20 0.41
CYP11B1 P15538 1/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP2A6 P11509 1/20 0.41
ALK Q9UM73 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25912057 0.83 ALDH1A1 (0.47) TRPM4CYP11B1HPGDMAPK1TSHR
SCHEMBL25356031 0.81 TRPM4 (0.55) TRPM4NQO2CYP11B1MEN1MAPT
SCHEMBL26021801 0.79 TRPM4 (0.50) TRPM4CYP11B1MEN1MAPTHPGD
SCHEMBL7171942 0.79 TRPM4 (0.61) TRPM4IDO1NQO2CYP11B1MEN1
SCHEMBL30789834 0.79 TRPM4 (0.42) TRPM4CYP11B1HPGDMAPK1TSHR
SCHEMBL20414478 0.79 TRPM4 (0.42) TRPM4IDO1CYP11B1HPGDMAPK1
SCHEMBL25905117 0.79 TRPM4 (0.52) TRPM4HSP90AA1HSP90AB1IDO1NQO2
SCHEMBL25081447 0.79 TRPM4 (0.42) TRPM4CYP11B1HPGDMAPK1TSHR
SCHEMBL17577281 0.79 TRPM4 (0.42) TRPM4HSP90AA1NQO2MAPTTSHR
SCHEMBL24115651 0.78 TRPM4 (0.52) TRPM4CDK9HSP90AA1HSP90AB1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220020932-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-01-20 US disclosed
WO-2020101169-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020932-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, OR51E2, OR10J3 TRPM4 111/4885CDK9 1386/4885HSP90AA1 4782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.