SCHEMBL17577281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17702476	0.89	DHODH (0.39)	TRPM4HSD17B10ALDH1A1TSHRCYP3A4
	SCHEMBL17658611	0.89	MGAM (0.38)	TRPM4TDP1CYP2A6GRM2GAA
	SCHEMBL15600491	0.83	TRPM4 (0.63)	TRPM4HSD17B10ALDH1A1TSHRCYP3A4
	SCHEMBL22019088	0.79	TRPM4 (0.57)	TRPM4HSD17B10TSHRCYP2A6HSP90AA1
	SCHEMBL18607421	0.79	ALDH1A1 (0.47)	HSD17B10ALDH1A1TSHRTDP1CYP2A6
	SCHEMBL18607688	0.78	KMT2A (0.51)	HSD17B10ALDH1A1CYP2A6HIF1ACYP1B1
	SCHEMBL17577283	0.77	HSP90AA1 (0.43)	HSD17B10ALDH1A1CYP3A4HSP90AA1MAPT
	SCHEMBL17265422	0.76	CXCR2 (0.43)	HSD17B10ALDH1A1TSHRCYP3A4TDP1
	SCHEMBL339112	0.76	HSD17B10 (0.65)	HSD17B10ALDH1A1TSHRCYP3A4TDP1
	SCHEMBL25912057	0.76	ALDH1A1 (0.47)	TRPM4HSD17B10ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.