Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 4/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962448 | 1.00 | KRAS (0.41) | KRASKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL21962682 | 0.88 | NR1H2 (0.39) | ROCK2MLYCD | |
| SCHEMBL22019320 | 0.88 | NR1H2 (0.39) | ROCK2MLYCD | |
| SCHEMBL21962690 | 0.86 | CPT2 (0.39) | TSHRLMNAHTTMLYCD | |
| SCHEMBL22019317 | 0.86 | CPT2 (0.39) | TSHRLMNAHTTMLYCD | |
| SCHEMBL22019319 | 0.85 | VNN1 (0.42) | NUDT1TSHRLMNAVNN1 | |
| SCHEMBL21962626 | 0.85 | VNN1 (0.42) | NUDT1TSHRLMNAVNN1 | |
| SCHEMBL22020535 | 0.84 | VNN1 (0.44) | ROCK2VNN1MLYCDHDAC8HDAC6 | |
| SCHEMBL21962341 | 0.84 | VNN1 (0.44) | ROCK2VNN1MLYCDHDAC8HDAC6 | |
| SCHEMBL22020531 | 0.83 | GRM5 (0.43) | NUDT1GCKHTTVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |