SCHEMBL22019188

CNC(=O)CC[C@H](NC(=O)CNC(=O)[C@@H]1C[C@H](O)CN1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	5/20	0.46

▸	RAMP3	O60896	9/20	0.41

▸	CALCR	P30988	9/20	0.41

▸	NTSR1	P30989	1/20	0.40

▸	REN	P00797	1/20	0.40

▸	NAA50	Q9GZZ1	1/20	0.40

▸	OPRD1	P41143	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29308439	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018809	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018314	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018380	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018810	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018363	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018370	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018340	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018502	0.95	APLNR (0.48)	APLNRRAMP3CALCRNTSR1NAA50
SCHEMBL22018359	0.94	APLNR (0.45)	APLNRRAMP3CALCRNTSR1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020099925-A2	PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES	YUYU PHARMA, INC. (KR)	2020-05-22	—	—	WO	disclosed