Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019629 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22019615 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22019635 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL13831366 | 0.83 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL13832044 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL22018951 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22019627 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22019357 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1HSD17B10TP53LMNA | |
| SCHEMBL22019621 | 0.81 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22018576 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |