Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018951 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL22019359 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL13832029 | 0.84 | NPSR1 (0.54) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL22019629 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL15986448 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL22019635 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL22019616 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KDM4ETP53TSHR | |
| SCHEMBL22019627 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL22019621 | 0.78 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL22018576 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |