Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019402 | 0.86 | SMN1; SMN2 (0.46) | POLBSMN1; SMN2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL14478848 | 0.70 | KDM4E (0.81) | LMNAPOLBSMN1; SMN2GAACYP3A4 | |
| SCHEMBL19420130 | 0.68 | L3MBTL1 (0.81) | LMNASMN1; SMN2GAACYP3A4CYP2C9 | |
| SCHEMBL22019404 | 0.68 | SMN1; SMN2 (0.34) | POLBSMN1; SMN2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL22019392 | 0.68 | SMN1; SMN2 (0.34) | POLBSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL22019395 | 0.67 | SMN1; SMN2 (0.33) | POLBSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL22018538 | 0.64 | SMN1; SMN2 (0.46) | POLBSMN1; SMN2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL21340632 | 0.62 | SMN1; SMN2 (0.59) | LMNAPOLBSMN1; SMN2GAACYP3A4 | |
| SCHEMBL22019622 | 0.61 | CYP2C19 (0.45) | POLBSMN1; SMN2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL22018990 | 0.60 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |