Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018990 | 0.79 | SMN1; SMN2 (0.47) | CYP2C19POLBSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL22019619 | 0.79 | ALDH1A1 (0.62) | CYP2C19POLBSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL22018538 | 0.78 | SMN1; SMN2 (0.46) | CYP2C19POLBSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL22019402 | 0.74 | SMN1; SMN2 (0.46) | CYP2C19POLBSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL22019633 | 0.69 | SMN1; SMN2 (0.44) | CYP2C19POLBSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL22019621 | 0.66 | ALDH1A1 (0.73) | SMN1; SMN2HSD17B10ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL22019391 | 0.64 | ALDH1A1 (0.74) | CYP2C19POLBSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL22019375 | 0.64 | SMN1; SMN2 (0.45) | CYP2C19POLBSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL22018576 | 0.63 | SMN1; SMN2 (0.64) | POLBSMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL11887664 | 0.63 | ALDH1A1 (0.67) | SMN1; SMN2HSD17B10ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |