Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019402 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL22019392 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL22019395 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL22046602 | 0.70 | ALDH1A1 (0.58) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL22019396 | 0.68 | LMNA (0.49) | SMN1; SMN2POLBCYP3A4ALDH1A1KDM4E | |
| SCHEMBL22018773 | 0.66 | RIPK1 (0.31) | — | |
| SCHEMBL22018538 | 0.58 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL22019403 | 0.58 | ALDH1A1 (0.60) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL22019622 | 0.56 | CYP2C19 (0.45) | SMN1; SMN2CYP2C19POLBCYP1A2CYP3A4 | |
| SCHEMBL7461113 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |