Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019436 | 0.89 | EPHX2 (0.41) | EPHX2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13569686 | 0.89 | EPHX2 (0.40) | EPHX2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4277690 | 0.89 | KCNH2 (0.48) | EPHX2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20056384 | 0.85 | EPHX2 (0.39) | EPHX2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4279308 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL26790048 | 0.70 | EPHX2 (0.55) | EPHX2KDM4EALDH1A1HSD17B10EGFR | |
| SCHEMBL9891900 | 0.69 | EPHX2 (0.53) | EPHX2ALDH1A1PDE10ALMNA | |
| SCHEMBL2755867 | 0.68 | EPHX2 (0.58) | EPHX2ALDH1A1EGFRPDE10ALMNA | |
| SCHEMBL1964743 | 0.68 | EPHX2 (0.52) | EPHX2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4273047 | 0.67 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | PRAXIS PREC MEDICINES INC (US) | 2020-05-20 | — | — | EP | disclosed |