Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277690 | 0.90 | KCNH2 (0.48) | EPHX2KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL22019435 | 0.89 | EPHX2 (0.42) | EPHX2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL20056384 | 0.88 | EPHX2 (0.39) | EPHX2KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL22019436 | 0.84 | EPHX2 (0.41) | EPHX2KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL4279308 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1HPGDKCNH2CACNA1I | |
| SCHEMBL13569862 | 0.70 | MEN1 (0.53) | EPHX2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL4273047 | 0.69 | KCNH2 (0.45) | KDM4EALDH1A1HPGDKCNH2CACNA1I | |
| SCHEMBL16133691 | 0.69 | EPHX2 (0.53) | EPHX2ALDH1A1KMT2AEGFRPDE10A | |
| SCHEMBL26790048 | 0.68 | EPHX2 (0.55) | EPHX2KDM4EALDH1A1HSD17B10EGFR | |
| SCHEMBL13569690 | 0.67 | LMNA (0.47) | ALDH1A1KMT2ATP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |