Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019435 | 0.89 | EPHX2 (0.42) | EPHX2AADATKDM4EPDE10AEGFR | |
| SCHEMBL4277690 | 0.87 | KCNH2 (0.48) | EPHX2AADATKDM4EPDE10AEGFR | |
| SCHEMBL13569686 | 0.84 | EPHX2 (0.40) | EPHX2AADATKDM4EPDE10AEGFR | |
| SCHEMBL20056384 | 0.83 | EPHX2 (0.39) | EPHX2AADATKDM4EPDE10AEGFR | |
| SCHEMBL22019438 | 0.77 | EPHX2 (0.42) | EPHX2AADATPDE10ASLC18A3HPGD | |
| SCHEMBL17285624 | 0.75 | ADRA2A (0.42) | KDM4ESLC18A3ALDH1A1PRMT5WDR77 | |
| SCHEMBL26790048 | 0.71 | EPHX2 (0.55) | EPHX2KDM4EPDE10AEGFRALDH1A1 | |
| SCHEMBL4279308 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL22020141 | 0.67 | USP30 (0.61) | EPHX2SLC18A3ALDH1A1KMT2AFPR2 | |
| SCHEMBL2755867 | 0.67 | EPHX2 (0.58) | EPHX2PDE10AEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | PRAXIS PREC MEDICINES INC (US) | 2020-05-20 | — | — | EP | disclosed |