SCHEMBL4277690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13569686	0.90	EPHX2 (0.40)	KCNH2CACNA1IEPHX2KDM4EALDH1A1
	SCHEMBL22019435	0.89	EPHX2 (0.42)	EPHX2KDM4EALDH1A1HPGDKMT2A
	SCHEMBL20056384	0.88	EPHX2 (0.39)	KCNH2CACNA1IEPHX2KDM4EALDH1A1
	SCHEMBL22019436	0.87	EPHX2 (0.41)	KCNH2CACNA1IEPHX2KDM4EALDH1A1
	SCHEMBL4279308	0.83	KDM4E (0.50)	KCNH2CACNA1IKDM4EALDH1A1HPGD
	SCHEMBL4273047	0.80	KCNH2 (0.45)	KCNH2CACNA1IKDM4EALDH1A1HPGD
	SCHEMBL4280615	0.78	KCNH2 (0.45)	KCNH2CACNA1IEPHX2HPGDKMT2A
	SCHEMBL8374007	0.76	KCNH2 (0.44)	KCNH2CACNA1IKDM4EALDH1A1HPGD
	SCHEMBL4269225	0.74	KCNH2 (0.46)	KCNH2CACNA1IKDM4EALDH1A1KMT2A
	SCHEMBL4278333	0.73	RAB9A (0.45)	KCNH2CACNA1IKMT2AMCHR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.