Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018671 | 0.92 | PSMB5 (0.53) | RECQLPSMB5GAAFAAHMEN1 | |
| SCHEMBL22018851 | 0.88 | PSMB5 (0.47) | PSMB5GAAEPHX2FAAHMEN1 | |
| SCHEMBL27175504 | 0.86 | PSMB5 (0.45) | PSMB5GAAFAAHMEN1MAPK1 | |
| SCHEMBL19656332 | 0.82 | RECQL (0.59) | RECQLGAAEPHX2FAAHDGKA | |
| SCHEMBL22064576 | 0.80 | RECQL (0.56) | RECQLPSMB5GAAFAAHMEN1 | |
| SCHEMBL18411703 | 0.80 | RECQL (0.56) | RECQLPSMB5GAAFAAHMEN1 | |
| SCHEMBL25122213 | 0.80 | RECQL (0.53) | RECQLPSMB5GAATSHR | |
| SCHEMBL22987342 | 0.80 | RECQL (0.53) | RECQLPSMB5GAATSHR | |
| SCHEMBL27175512 | 0.77 | PSMB5 (0.38) | PSMB5FAAHSMN1; SMN2 | |
| SCHEMBL7153526 | 0.77 | FAAH (0.61) | FAAHMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102053-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2020-05-22 | — | — | WO | disclosed |