Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019376 | 0.76 | SLC27A1 (0.54) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22018594 | 0.69 | ALDH1A1 (0.55) | CYP3A4ALDH1A1MAPTRORCRAB9A | |
| SCHEMBL22018522 | 0.67 | ALDH1A1 (0.55) | SMN1; SMN2POLBNPSR1ALDH1A1MAPT | |
| SCHEMBL22018990 | 0.65 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP2C19POLBCYP3A4CYP1A2 | |
| SCHEMBL22018538 | 0.64 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19POLBCYP3A4CYP1A2 | |
| SCHEMBL22019622 | 0.64 | CYP2C19 (0.45) | SMN1; SMN2CYP2C19POLBCYP3A4CYP1A2 | |
| SCHEMBL22019402 | 0.62 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19POLBCYP3A4CYP1A2 | |
| SCHEMBL23334063 | 0.61 | ALDH1A1 (0.59) | SMN1; SMN2POLBALDH1A1MAPTMEN1 | |
| SCHEMBL16160318 | 0.54 | L3MBTL1 (0.58) | CYP2C19POLBCYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL12160736 | 0.52 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19POLBCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |