Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954663 | 0.85 | CYP11B2 (0.50) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL16905570 | 0.82 | CHRNA1 (0.65) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL16955729 | 0.81 | HTR2C (0.35) | HTR2C | |
| SCHEMBL30963 | 0.79 | CYP11B2 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL19561507 | 0.78 | CYP11B2 (0.42) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL14290362 | 0.78 | CYP11B2 (0.49) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL10088668 | 0.78 | CYP11B2 (0.49) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL25385512 | 0.77 | CHRNA1 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL2695090 | 0.77 | CHRNA1 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL1081422 | 0.77 | NOS3 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098876-A1 | CARBONYL SUBSTITUTED DIAZASPIRO COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023016518-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2023-02-16 | — | — | WO | disclosed |
| US-11369605-B2 | Optically active azabicyclo ring derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-06-28 | — | — | US | disclosed |
| US-20210338668-A1 | OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-11-04 | — | — | US | disclosed |
| US-10815241-B2 | Optically active azabicyclo ring derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-27 | — | — | US | disclosed |
| US-20200157114-A1 | OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11369605-B2 | Optically active azabicyclo ring derivative | MLLT3, MEN1, MLLT1 | CHRNA1 3198/4885CHRNG 4174/4885CHRNB1 3106/4885 |
| US-20210338668-A1 | OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE | MLLT3, MEN1, MLLT1 | CHRNA1 3198/4885CHRNG 4174/4885CHRNB1 3106/4885 |
| US-20200157114-A1 | OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE | MLLT3, MEN1, MLLT1 | CHRNA1 3198/4885CHRNG 4174/4885CHRNB1 3106/4885 |
| US-10815241-B2 | Optically active azabicyclo ring derivative | MLLT3, MEN1, MLLT1 | CHRNA1 3198/4885CHRNG 4174/4885CHRNB1 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.