Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954663 | 0.93 | CYP11B2 (0.50) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL14290362 | 0.86 | CYP11B2 (0.49) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10088668 | 0.86 | CYP11B2 (0.49) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL2175583 | 0.83 | HTR2C (0.54) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL2320589 | 0.82 | CYP11B2 (0.45) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL1366189 | 0.82 | CYP11B2 (0.48) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL22019658 | 0.79 | CHRNA1 (0.46) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL11894025 | 0.78 | CYP11B2 (0.44) | CYP11B2CYP11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL16905570 | 0.76 | CHRNA1 (0.65) | CYP11B2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL16960487 | 0.75 | NOTUM (0.38) | CYP11B2CYP11B1FASNHTR2CNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |