Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | RRM2 | P31350 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38655755 | 0.80 | NOS3 (0.37) | UHRF1 | |
| SCHEMBL22725617 | 0.80 | NOS3 (0.37) | UHRF1 | |
| SCHEMBL24126875 | 0.80 | ALDH1A1 (0.41) | UHRF1 | |
| SCHEMBL14145764 | 0.80 | NOS3 (0.45) | UHRF1 | |
| SCHEMBL18865684 | 0.78 | ALDH1A1 (0.31) | UHRF1 | |
| SCHEMBL12248257 | 0.78 | IDO1 (0.35) | — | |
| SCHEMBL31188331 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL20099831 | 0.78 | HTT (0.43) | UHRF1 | |
| SCHEMBL23510806 | 0.75 | P2RX3 (0.40) | — | |
| SCHEMBL25181915 | 0.74 | GCGR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |