SCHEMBL2202189

SCHEMBL2202189

Nc1ccc(O)c(O)c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.44
KAT2B Q92831 2/20 0.44
KAT8 Q9H7Z6 2/20 0.44
IDO1 P14902 2/20 0.44
HDAC3 O15379 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CSNK2A3 Q8NEV1 1/20 0.42
ALOX15 P16050 6/20 0.42
HSD17B10 Q99714 5/20 0.42
CYP3A4 P08684 1/20 0.42
ALDH1A1 P00352 5/20 0.39
HPGD P15428 4/20 0.39
GAA P10253 4/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 3/20 0.39
ALOX12 P18054 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530989 1.00 EP300 (0.44) EP300KAT2BKAT8IDO1HDAC3
Hydrochloric Acid SCHEMBL29617043 0.97 EP300 (0.42) EP300KAT2BKAT8IDO1HDAC3
Hydrochloric Acid SCHEMBL4945018 0.97 EP300 (0.42) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL632398 0.81 ALDH1A1 (0.42) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL4958689 0.81 ALOX15 (0.39) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL28942714 0.79 CSNK2A2 (0.56) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL31256663 0.79 EP300 (0.46) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL29810844 0.79 IDO1 (0.46) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL632499 0.79 EP300 (0.46) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL29660908 0.79 CSNK2A2 (0.56) EP300KAT2BKAT8IDO1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114672020-B Preparation method of benzoxazinyl conjugated trapezoid polymer and application of benzoxazinyl conjugated trapezoid polymer in hydrogen sulfide detection 天津科技大学 2023-10-20 CN claimed
CN-114672020-A Preparation method of benzoxazine-based conjugated trapezoidal polymer and application of benzoxazine-based conjugated trapezoidal polymer in hydrogen sulfide detection 天津科技大学 2022-06-28 CN claimed
CN-105503847-A Method for synthesizing benzodioxazole type compound LANZHOU INST CHEMICAL PHYSICS CAS 2016-04-20 CN claimed
CN-101024724-B Polymer electrolyte membrane, method of manufacturing the same and fuel cell including the same SAMSUNG SDI CO LTD 2010-12-08 CN claimed
US-7396778-B2 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-07-08 US claimed
CN-101024724-A Polymer electrolyte membrane, method of manufacturing the same and fuel cell including the same SAMSUNG SDI CO LTD (KR) 2007-08-29 CN claimed
US-20050245097-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-11-03 US claimed
US-6936552-B2 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-08-30 US claimed
EP-1493771-A1 METHOD OF SYNTHESIZING POLYMERIC MATERIAL, METHOD OF FORMING THIN POLYMER FILM, AND METHOD OF FORMING INTERLAYER DIELECTRIC MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-01-05 EP claimed
US-20040087182-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD 2004-05-06 US claimed
EP-1024407-A1 POSITIVE PHOTOSENSITIVE POLYIMIDE COMPOSITION PI R & D Co Ltd (JP) 2000-08-02 EP claimed
EP-0412301-B1 Boron nitride membrane in wafer structure REDWOOD MICROSYSTEMS INC (US) 1994-12-07 EP claimed
US-4965336-A PHENYLIMIDE ACID HALIDE ENCAPPED POLYBENZOXAZLES; CURABLE, SOLVENT RESISTANCE PREPREGS THE BOEING COMPANY (US) 1990-10-23 US claimed
US-4888027-A Process for dyeing keratinous fibers with 5,6-dihydroxyindole in combination with an iodide and a hydrogen peroxide composition at alkaline pH L'OREAL (FR) 1989-12-19 US claimed
EP-0309649-A2 High performance heterocycle oligomers and blends THE BOEING COMPANY (US) 1989-04-05 EP claimed
CN-87107214-A High purity 4,6-diaminostilbene, the preparation method of 3-dihydroxy-benzene 1988-06-15 CN claimed
CN-114672020-B Preparation method of benzoxazinyl conjugated trapezoid polymer and application of benzoxazinyl conjugated trapezoid polymer in hydrogen sulfide detection 天津科技大学 2023-10-20 CN disclosed
CN-114672020-B Preparation method of benzoxazinyl conjugated trapezoid polymer and application of benzoxazinyl conjugated trapezoid polymer in hydrogen sulfide detection 天津科技大学 2023-10-20 CN disclosed
US-4631331-A BENZO-N-HETEROCYCLES THE DOW CHEMICAL COMPANY (US) 1986-12-23 US disclosed
US-4307507-A Method of manufacturing a field-emission cathode structure THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1981-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245097-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film PARG, STOM, DNMT1 EP300 1852/4885KAT2B 839/4885KAT8 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.