Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.42 |
| ▸ | GAA known ✓ | P10253 | 4/20 | 0.38 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.38 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29617043 | 1.00 | EP300 (0.42) | EP300KAT2BKAT8HDAC3IDO1 | |
| Hydrochloric Acid SCHEMBL27497475 | 1.00 | EP300 (0.42) | EP300KAT2BKAT8HDAC3IDO1 | |
| SCHEMBL30530989 | 0.97 | EP300 (0.44) | EP300KAT2BKAT8HDAC3IDO1 | |
| SCHEMBL2202189 | 0.97 | EP300 (0.44) | EP300KAT2BKAT8HDAC3IDO1 | |
| Hydrochloric Acid SCHEMBL11791228 | 0.80 | IDO1 (0.44) | EP300KAT2BKAT8HDAC3IDO1 | |
| SCHEMBL632398 | 0.79 | ALDH1A1 (0.42) | EP300KAT2BKAT8HDAC3IDO1 | |
| SCHEMBL4958689 | 0.79 | ALOX15 (0.39) | EP300KAT2BKAT8HDAC3IDO1 | |
| Hydrochloric Acid SCHEMBL4653071 | 0.78 | EP300 (0.42) | EP300KAT2BKAT8HDAC3IDO1 | |
| Hydrochloric Acid SCHEMBL8694604 | 0.78 | EP300 (0.42) | EP300KAT2BKAT8HDAC3IDO1 | |
| Hydrochloric Acid SCHEMBL30445419 | 0.78 | EP300 (0.42) | EP300KAT2BKAT8HDAC3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080069974-A1 | Liquid crystal display panel and fabricating method thereof | LG.PHILIPS LCD CO., LTD. | 2008-03-20 | — | — | US | claimed |
| US-11472923-B2 | Nanoparticle catalyst for synthesizing polybenzoxazole with controlled polymerization | BROWN UNIVERSITY (US) | 2022-10-18 | — | — | US | disclosed |
| US-20220162389-A1 | NANOPARTICLE CATALYST FOR SYNTHESIZING POLYBENZOXAZOLE WITH CONTROLLED POLYMERIZATION | BROWN UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
| WO-2020198247-A1 | NANOPARTICLE CATALYST FOR SYNTHESIZING POLYBENZOXAZOLE WITH CONTROLLED POLYMERIZATION | BROWN UNIVERSITY (US) | 2020-10-01 | — | — | WO | disclosed |
| US-20080069974-A1 | Liquid crystal display panel and fabricating method thereof | LG.PHILIPS LCD CO., LTD. | 2008-03-20 | — | — | US | disclosed |
| US-6114498-A | Benzobisazole polymers containing 2,2'-bipyridine-5,5 '-diyl moieties | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2000-09-05 | — | — | US | disclosed |
| US-5633337-A | Aromatic benzobisazole polymers and copolymers incorporating diphenylamino moieties | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1997-05-27 | — | — | US | disclosed |
| US-5536866-A | Triarylamine-based dinitrile and dicarboxylic acid monomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-07-16 | — | — | US | disclosed |
| US-5534613-A | ELECTROCONDUCTORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-07-09 | — | — | US | disclosed |
| US-5521277-A | ELECTROCONDUCTIVE POLYMERS WITH POLYTHIAZOLES OR POLYOXAZOLE GROUPS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-05-28 | — | — | US | disclosed |
| US-5200495-A | Rigid-rod benzobisazole polymer containing cyclic phosphate ester | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1993-04-06 | — | — | US | disclosed |
| US-5175232-A | Rigid-rod benzobisazole copolymer containing cyclic phosphate ester | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-12-29 | — | — | US | disclosed |