SCHEMBL22022981

SCHEMBL22022981

CCCCCCCCC=CCCCCCCCCOCCNCCCCCCCCCCCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 1/20 0.50
▸ FAAH O00519 2/20 0.47
▸ TRPV1 Q8NER1 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ PPARA Q07869 2/20 0.45
▸ LPAR1 Q92633 1/20 0.45
▸ LPAR2 Q9HBW0 1/20 0.45
▸ LPAR3 Q9UBY5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20030172 1.00 EPHX2 (0.50) EPHX2FAAHTRPV1ALDH1A1TSHR
SCHEMBL22022994 1.00 EPHX2 (0.50) EPHX2FAAHTRPV1ALDH1A1TSHR
SCHEMBL22814028 1.00 EPHX2 (0.50) EPHX2FAAHTRPV1ALDH1A1TSHR
SCHEMBL15616007 1.00 EPHX2 (0.50) EPHX2FAAHTRPV1ALDH1A1TSHR
SCHEMBL20030173 1.00 EPHX2 (0.50) EPHX2FAAHTRPV1ALDH1A1TSHR
SCHEMBL20030175 1.00 EPHX2 (0.50) EPHX2FAAHTRPV1ALDH1A1TSHR
SCHEMBL12179827 0.96 FAAH (0.50) EPHX2FAAHTRPV1LPAR1LPAR2
SCHEMBL12179809 0.96 FAAH (0.50) EPHX2FAAHTRPV1LPAR1LPAR2
SCHEMBL20017981 0.96 FAAH (0.50) EPHX2FAAHTRPV1LPAR1LPAR2
SCHEMBL12179849 0.96 FAAH (0.50) EPHX2FAAHTRPV1LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633365-B2 Nucleic acid-containing lipid nanoparticle KYOWA KIRIN CO., LTD. (JP) 2023-04-25 — — US disclosed
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE KYOWA KIRIN CO., LTD. (JP) 2020-11-26 — — US disclosed
EP-3662913-A1 NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES Kyowa Kirin Co., Ltd. (JP) 2020-06-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633365-B2 Nucleic acid-containing lipid nanoparticle LIPA, LIPC, PNLIP EPHX2 1410/4885FAAH 89/4885TRPV1 3502/4885
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE LIPA, LIPC, PNLIP EPHX2 1410/4885FAAH 89/4885TRPV1 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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