SCHEMBL220264

SCHEMBL220264

CC(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
KDM4E B2RXH2 2/20 0.67
MEN1 O00255 2/20 0.67
LMNA P02545 2/20 0.67
KMT2A Q03164 2/20 0.67
MPO P05164 1/20 0.67
TSHR P16473 1/20 0.67
BLM P54132 1/20 0.67
PMP22 Q01453 1/20 0.67
HIF1A Q16665 1/20 0.67
TACR1 P25103 2/20 0.64
HTR2A P28223 2/20 0.57
ADRB1 P08588 1/20 0.57
HTR1A P08908 1/20 0.57
ADRA2A P08913 1/20 0.57
SLC6A2 P23975 1/20 0.57
HTR1D P28221 1/20 0.57
HTR1B P28222 1/20 0.57
HTR2C P28335 1/20 0.57
HTR1E P28566 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534005 1.00 MAPT (0.67) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL29534060 0.99 KDM4E (0.65) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL6745399 0.99 MAPT (0.65) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL475351 0.92 MAPT (0.74) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL289044 0.92 MAPT (0.74) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL3873457 0.90 MAPT (0.64) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL21059260 0.89 MAPT (0.70) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL120931 0.88 KDM4E (0.69) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL5065255 0.88 KDM4E (0.65) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL17503190 0.88 MAPT (0.72) MAPTKDM4EMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114327-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-10 US claimed
CN-118652320-B Preparation method and application of instant recombinant human albumin freeze-dried 通化安睿特生物制药股份有限公司 2024-11-05 CN claimed
CN-118652320-A Preparation method and application of instant recombinant human albumin freeze-dried 通化安睿特生物制药股份有限公司 2024-09-17 CN claimed
CN-118512402-A Nanoparticle for delivering medicine in vivo and preparation method thereof 无锡市南京大学锡山应用生物技术研究所 2024-08-20 CN claimed
CN-117546833-A Preparation method of organoid frozen stock solution 云南昆大生物细胞科技有限公司 2024-02-13 CN claimed
US-20230398096-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-12-14 US claimed
CN-116801719-A Formulations for cryopreservation of PBMC SQZ生物技术公司 2023-09-22 CN claimed
CN-113980118-B Serum albumin degreasing method 广东卫伦生物制药有限公司 2023-06-06 CN claimed
CN-114514035-A Compositions and methods for delivering therapeutic biologies for treatment of diseases 伊勒卓菲公司 2022-05-17 CN claimed
CN-107907603-B Method for measuring tryptophan related substances in amino acid injection 华仁药业股份有限公司 2021-01-05 CN claimed
EP-1112091-A4 RAPID CRYOBARIC STERILIZATION AND VACCINE PREPARATION BBI BIOSEQ INC (US) 2001-08-01 EP claimed
EP-1112091-A1 RAPID CRYOBARIC STERILIZATION AND VACCINE PREPARATION BBI Bioseq, Inc. (US) 2001-07-04 EP claimed
EP-1095128-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2001-05-02 EP claimed
WO-2000048641-A1 RAPID CRYOBARIC STERILIZATION AND VACCINE PREPARATION BBI BIOSEQ, INC. (US) 2000-08-24 WO claimed
EP-1023899-A1 AQUEOUS PREPARATION CONTAINING ANTIVIRAL AGENT HAVING PURINE OR PYRIMIDINE SKELETON Wakamoto Pharmaceutical Co., Ltd. (JP) 2000-08-02 EP claimed
WO-2000002991-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO claimed
WO-2000002981-A2 LAUNDRY AND CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO claimed
EP-0971024-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP claimed
EP-0971025-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP claimed
US-6013773-A STABLE SOLUTION CONTAINING SOMATOTROPIN, NICOTINAMIDE AND SODIUM ACETYLTRYPTOPHANE ; FOR INCREASED SOLUBILITY OF SOMATOTROPIN MITSUI CHEMICALS, INC. (JP) 2000-01-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114327-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND ALK, ALPI, TTR MAPT 240/4885KDM4E 1970/4885MEN1 2674/4885
US-20230398096-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND ALK, ALPI, TTR MAPT 240/4885KDM4E 1970/4885MEN1 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.