SCHEMBL29534005

SCHEMBL29534005

CC(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
KDM4E B2RXH2 2/20 0.67
MEN1 O00255 2/20 0.67
LMNA P02545 2/20 0.67
KMT2A Q03164 2/20 0.67
MPO P05164 1/20 0.67
TSHR P16473 1/20 0.67
BLM P54132 1/20 0.67
PMP22 Q01453 1/20 0.67
HIF1A Q16665 1/20 0.67
TACR1 P25103 2/20 0.64
HTR2A P28223 2/20 0.57
ADRB1 P08588 1/20 0.57
HTR1A P08908 1/20 0.57
ADRA2A P08913 1/20 0.57
SLC6A2 P23975 1/20 0.57
HTR1D P28221 1/20 0.57
HTR1B P28222 1/20 0.57
HTR2C P28335 1/20 0.57
HTR1E P28566 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL220264 1.00 MAPT (0.67) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL29534060 0.99 KDM4E (0.65) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL6745399 0.99 MAPT (0.65) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL475351 0.92 MAPT (0.74) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL289044 0.92 MAPT (0.74) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL3873457 0.90 MAPT (0.64) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL21059260 0.89 MAPT (0.70) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL120931 0.88 KDM4E (0.69) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL5065255 0.88 KDM4E (0.65) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL17503190 0.88 MAPT (0.72) MAPTKDM4EMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748385-A1 BLOOD PLASMA FRACTIONS AS A TREATMENT FOR AGING-ASSOCIATED COGNITIVE DISORDERS Alkahest, Inc. (US) 2026-05-27 EP disclosed
EP-4719440-A1 COMPOSITIONS OF BLOOD PLASMA FRACTIONS AND BLOOD PLASMA SUBFRACTIONS AND THEIR USE IN TREATMENT OF DISEASE Alkahest, Inc. (US) 2026-04-08 EP disclosed
EP-4054597-B1 BLOOD PLASMA FRACTIONS FOR USE IN MUSCLE REGENERATION ALKAHEST INC (US) 2026-03-25 EP disclosed
EP-4689665-A1 COMPOSITIONS AND METHODS OF PREPARATION OF BLOOD PLASMA PRODUCTS WITH REDUCED LEVELS OF FCERISS AUTOANTIBODIES Grifols Worldwide Operations Limited (IE) 2026-02-11 EP disclosed
WO-2024258622-A9 BLOOD PLASMA FRACTIONS AS A TREATMENT FOR CHEMOTHERAPY INDUCED COGNITIVE DISORDERS ALKAHEST, INC. (US) 2025-11-13 WO disclosed
EP-4615488-A1 BLOOD PLASMA FRACTIONS FOR IMPROVEMENT OF MYELINATION Alkahest, Inc. (US) 2025-09-17 EP disclosed
WO-2025126144-A1 METHODS OF MONITORING PARAMETERS IN SOLUTION CSL BEHRING AG (CH) 2025-06-19 WO disclosed
EP-4353320-B1 BLOOD PLASMA AND PLASMA FRACTIONS AS THERAPY FOR TUMOR GROWTH AND PROGRESSION ALKAHEST INC (US) 2025-06-18 EP disclosed
WO-2024258622-A1 BLOOD PLASMA FRACTIONS AS A TREATMENT FOR CHEMOTHERAPY INDUCED COGNITIVE DISORDERS ALKAHEST, INC. (US) 2024-12-19 WO disclosed
US-20240409612-A1 IMPROVED PURIFICATION PROCESS CSL BEHRING AG (CH) 2024-12-12 US disclosed
WO-2022245552-A1 BLOOD PLASMA FRACTIONS FOR USE IN LIVER REGENERATION ALKAHEST, INC. (US) 2022-11-24 WO disclosed
US-11484551-B2 Method of treating liver failure with plasma fraction IV-4 ALKAHEST, INC. (US) 2022-11-01 US disclosed
EP-4061384-A1 BLOOD PLASMA FRACTIONS FOR USE IN LIVER REGENERATION Alkahest, Inc. (US) 2022-09-28 EP disclosed
EP-4054597-A1 BLOOD PLASMA FRACTIONS FOR USE IN MUSCLE REGENERATION Alkahest, Inc. (US) 2022-09-14 EP disclosed
US-11439687-B2 Blood plasma fractions for use in muscle regeneration ALKAHEST, INC. (US) 2022-09-13 US disclosed
US-11413308-B2 Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products ALKAHEST, INC. (US) 2022-08-16 US disclosed
US-20220152161-A1 Blood Plasma Fractions as a Treatment for Aging-Associated Cognitive Disorders ALKAHEST, INC. 2022-05-19 US disclosed
EP-3995141-A1 BLOOD PLASMA AND PLASMA FRACTIONS AS THERAPY FOR TUMOR GROWTH AND PROGRESSION Alkahest, Inc. (US) 2022-05-11 EP disclosed
EP-3995140-A1 BLOOD PLASMA FRACTIONS AS A TREATMENT FOR AGING-ASSOCIATED COGNITIVE DISORDERS Alkahest, Inc. (US) 2022-05-11 EP disclosed
US-11298377-B2 Methods of improving wound healing ALKAHEST, INC. (US) 2022-04-12 US disclosed