Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039172 | 0.87 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL19206406 | 0.87 | TSHR (0.34) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL1005044 | 0.76 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL29282852 | 0.76 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL14744528 | 0.76 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL14221891 | 0.76 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL13850355 | 0.73 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL17310016 | 0.72 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL8990154 | 0.72 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL222225 | 0.72 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016991-B1 | LIQUID MOLDING COMPOSITIONS | MATERIA INC (US) | 2024-06-12 | — | — | EP | claimed |
| US-20240116039-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2024-04-11 | — | — | US | claimed |
| EP-3256505-B1 | CYCLIC OLEFIN RESIN COMPOSITIONS COMPRISING FUNCTIONAL ELASTOMERS | MATERIA INC (US) | 2023-11-29 | — | — | EP | claimed |
| US-20230149911-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2023-05-18 | — | — | US | claimed |
| US-11577232-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO. KG (DE) | 2023-02-14 | — | — | US | claimed |
| US-20220118434-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2022-04-21 | — | — | US | claimed |
| US-11241680-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO. KG | 2022-02-08 | — | — | US | claimed |
| US-20210403654-A1 | ADHESION PROMOTER COMPOSITIONS FOR CYCLIC OLEFIN RESIN COMPOSITIONS | MATERIA, INC. (US) | 2021-12-30 | — | — | US | claimed |
| US-10907018-B2 | Adhesion promoter compositions for cyclic olefin resin compositions | MATERIA, INC. (US) | 2021-02-02 | — | — | US | claimed |
| US-10711090-B2 | Thermal insulation | MATERIA, INC. (US) | 2020-07-14 | — | — | US | claimed |
| US-7504465-B2 | Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-17 | — | — | US | claimed |
| US-20090062475-A1 | Production of elastomeric functionalized olefin polymers | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2009-03-05 | — | — | US | claimed |
| US-20080312393-A1 | Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof | BAUGH LISA S | 2008-12-18 | — | — | US | claimed |
| US-7268233-B2 | Nickel-carbene, palladium-carbene and platinum-carbene complexes, their production and use in catalytic reactions | UMICORE AG & CO. KG (DE) | 2007-09-11 | — | — | US | claimed |
| EP-1526917-B1 | NOVEL NICKEL-CARBENE, PALLADIUM-CARBENE AND PLATINUM-CARBENE COMPLEXES, THEIR PRODUCTION AND USE IN CATALYTIC REACTIONS | UMICORE AG & CO KG (DE) | 2007-03-14 | — | — | EP | claimed |
| EP-1704172-A1 | LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF | ExxonMobil Research and Engineering Company (US) | 2006-09-27 | — | — | EP | claimed |
| US-20060128935-A1 | Manufacture of macrocyclic polyester oligomers | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-06-15 | — | — | US | claimed |
| US-20060122398-A1 | Novel nickel-carbene, palladium-carbene and platinum-carbene complexes, their produciton and use in catalytic reactions | UMICORE AG & CO. KG (DE) | 2006-06-08 | — | — | US | claimed |
| WO-2005063834-A1 | LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-07-14 | — | — | WO | claimed |
| US-20050137369-A1 | Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2005-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241680-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRG2 3496/4885GABRB3 2335/4885 |
| US-20230149911-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRG2 3496/4885GABRB3 2335/4885 |
| US-11577232-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRG2 3496/4885GABRB3 2335/4885 |
| US-20240116039-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRG2 3496/4885GABRB3 2335/4885 |
| US-20220118434-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRG2 3496/4885GABRB3 2335/4885 |
| US-20060122398-A1 | Novel nickel-carbene, palladium-carbene and platinum-carbene complexes, their produciton and use in catalytic reactions | PPOX, PDCD1, PDCD1LG2 | GABRA1 4236/4885GABRG2 4208/4885GABRB3 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.