Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682032 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31682008 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31682081 | 0.92 | HDAC1 (0.43) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31681996 | 0.92 | HDAC1 (0.43) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31682002 | 0.92 | HDAC1 (0.43) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31681986 | 0.92 | HDAC1 (0.43) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31682075 | 0.92 | HDAC1 (0.43) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL31682033 | 0.92 | HDAC1 (0.43) | SMN1; SMN2PKMCA2CA12CA1 | |
| SCHEMBL22029360 | 0.92 | ALDH1A1 (0.37) | SMN1; SMN2PKMCA2CA1HDAC1 | |
| SCHEMBL31682112 | 0.92 | ALDH1A1 (0.37) | SMN1; SMN2PKMCA2CA1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893934-B1 | INSULIN CONJUGATES | SANOFI SA (FR) | 2025-09-10 | — | — | EP | disclosed |
| US-12195510-B2 | Insulin conjugates | SANOFI (FR) | 2025-01-14 | — | — | US | disclosed |
| US-20230346949-A1 | A METHOD OF FORMING A CONJUGATE OF A SULFONAMIDE AND A POLYPEPTIDE | SANOFI SA (FR) | 2023-11-02 | — | — | US | disclosed |
| US-20230346949-A1 | A METHOD OF FORMING A CONJUGATE OF A SULFONAMIDE AND A POLYPEPTIDE | SANOFI SA (FR) | 2023-11-02 | — | — | US | disclosed |
| EP-4073096-A1 | A METHOD OF FORMING A CONJUGATE OF A SULFONAMIDE AND A POLYPEPTIDE | SANOFI (FR) | 2022-10-19 | — | — | EP | disclosed |
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
| EP-3893934-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2021-10-20 | — | — | EP | disclosed |
| EP-3894391-A1 | PEPTIDE BINDER | SANOFI (FR) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020120463-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020120479-A1 | PEPTIDE BINDER | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | SMN1; SMN2 1332/4885PKM 1743/4885CA2 1521/4885 |
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | SMN1; SMN2 1332/4885PKM 1743/4885CA2 1521/4885 |
| US-20230346949-A1 | A METHOD OF FORMING A CONJUGATE OF A SULFONAMIDE AND A POLYPEPTIDE | IAPP, AMY2A, STS | SMN1; SMN2 1639/4885PKM 2257/4885CA2 1149/4885 |
| US-12195510-B2 | Insulin conjugates | IAPP, INSR, IGF1R | SMN1; SMN2 1332/4885PKM 1743/4885CA2 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.