Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107363 | 0.88 | TSHR (0.51) | CNR1CNR2MAPTRAB9AL3MBTL1 | |
| SCHEMBL16107035 | 0.81 | SMN1; SMN2 (0.53) | RAB9AUSP2KDM4EKMT2AMEN1 | |
| SCHEMBL8801038 | 0.76 | CES2 (0.54) | MAPTRAB9AKDM4ENPC1KMT2A | |
| SCHEMBL1712444 | 0.73 | TSHR (0.56) | MAPTRAB9AUSP2L3MBTL1KDM4E | |
| SCHEMBL12325069 | 0.72 | HSP90AA1 (0.56) | MAPTRAB9AKDM4ETSHRKMT2A | |
| SCHEMBL31449995 | 0.71 | SLC6A4 (0.50) | MAPTRAB9AL3MBTL1KDM4ENPC1 | |
| SCHEMBL1712613 | 0.71 | TSHR (0.53) | MAPTUSP2KDM4ETSHRKMT2A | |
| SCHEMBL16871335 | 0.71 | SLC6A3 (0.65) | CNR1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL7611832 | 0.70 | PPARG (0.52) | MAPTRAB9AUSP2L3MBTL1KDM4E | |
| SCHEMBL29114924 | 0.70 | SCN1A (0.57) | KMT2AMEN1LMNAADORA3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200163937-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163937-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | NAT1, CYP2C19, CYP3A5 | CNR1 562/4885CNR2 571/4885MAPT 1075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.