Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22031451 | 0.94 | CNR2 (0.36) | CNR2PIK3C3 | |
| SCHEMBL29671115 | 0.94 | CNR2 (0.36) | CNR2PIK3C3 | |
| SCHEMBL22016612 | 0.90 | PIK3C3 (0.32) | PIK3C3 | |
| SCHEMBL22016611 | 0.90 | PIK3C3 (0.32) | PIK3C3 | |
| SCHEMBL21978829 | 0.88 | ROCK2 (0.33) | CNR2PIK3C3 | |
| SCHEMBL21978831 | 0.88 | ROCK2 (0.33) | CNR2PIK3C3 | |
| SCHEMBL21978822 | 0.88 | ROCK2 (0.33) | CNR2PIK3C3 | |
| SCHEMBL22016721 | 0.87 | ITGB1 (0.33) | PIK3C3 | |
| SCHEMBL22016557 | 0.86 | CNR2 (0.31) | CNR2 | |
| SCHEMBL22035515 | 0.85 | CNR2 (0.36) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11179383-B2 | Compounds for inhibition of α4β7 integrin | GILEAD SCIENCES, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200163953-A1 | Compounds for Inhibition of Alpha 4 Beta 7 Integrin | GILEAD SCIENCES, INC. | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163953-A1 | Compounds for Inhibition of Alpha 4 Beta 7 Integrin | ITGB7, ITGB4, ITGA4 | CNR2 3604/4885PIK3C3 2285/4885 |
| US-11179383-B2 | Compounds for inhibition of α4β7 integrin | ITGB7, ITGB4, ITGA4 | CNR2 3501/4885PIK3C3 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.