Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036440 | 1.00 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL21980046 | 0.77 | CHRNB2 (0.46) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL25795661 | 0.75 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL27053456 | 0.75 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL3445529 | 0.68 | HTR2C (0.68) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL27274450 | 0.65 | CHRNB2 (0.68) | CHRNB2CHRNA4HTR2CNOS3NOS1 | |
| SCHEMBL11530896 | 0.65 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL27384793 | 0.65 | CHRNB2 (0.42) | CHRNB2CHRNA4HTR2CACHECYP1A2 | |
| SCHEMBL16958181 | 0.64 | CHRNB2 (0.61) | CHRNB2CHRNA4HTR2CNOS3NOS1 | |
| SCHEMBL3692444 | 0.64 | CHRNB2 (0.41) | CHRNB2CHRNA4HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165189-A1 | PSEUDO TRÖGER'S BASE AMINES AND MICROPOROUS POLYMERS DERIVED FROM PSEUDO TRÖGER'S BASE AMINES | UNIV KING ABDULLAH SCI & TECH (SA) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165189-A1 | PSEUDO TRÖGER'S BASE AMINES AND MICROPOROUS POLYMERS DERIVED FROM PSEUDO TRÖGER'S BASE AMINES | PARG, PARN, TPR | CHRNB2 1422/4885CHRNA4 1331/4885HTR2C 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.