Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | UGT2B17 | O75795 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795661 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL27053456 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL22035375 | 0.77 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL22036440 | 0.77 | CHRNB2 (0.44) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL23222447 | 0.70 | DYRK1A (0.39) | CHRNB2CHRNA4KMT2AACHETRPA1 | |
| SCHEMBL3445529 | 0.70 | HTR2C (0.68) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL14591153 | 0.67 | KMT2A (0.44) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL25554156 | 0.67 | CHRNB2 (0.43) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL16502234 | 0.67 | CHRNB2 (0.38) | CHRNB2CHRNA4HTR2CKMT2AHTR2A | |
| SCHEMBL11530896 | 0.67 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2CKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165189-A1 | PSEUDO TRÖGER'S BASE AMINES AND MICROPOROUS POLYMERS DERIVED FROM PSEUDO TRÖGER'S BASE AMINES | UNIV KING ABDULLAH SCI & TECH (SA) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165189-A1 | PSEUDO TRÖGER'S BASE AMINES AND MICROPOROUS POLYMERS DERIVED FROM PSEUDO TRÖGER'S BASE AMINES | PARG, PARN, TPR | CHRNB2 1422/4885CHRNA4 1331/4885HTR2C 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.