SCHEMBL22036088

SCHEMBL22036088

COC(=O)C(Cc1ccc(N)cc1)NC(=O)c1ccc(N=C=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LNPEP Q9UIQ6 8/20 0.55
▸ RAB9A P51151 2/20 0.50
▸ GAA P10253 1/20 0.50
▸ CA2 P00918 2/20 0.48
▸ TYMS P04818 1/20 0.47
▸ ERAP2 Q6P179 7/20 0.47
▸ ERAP1 Q9NZ08 5/20 0.47
▸ NPC1 O15118 1/20 0.45
▸ TAS1R3 Q7RTX0 1/20 0.45
▸ TAS1R1 Q7RTX1 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ GLA P06280 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11907538 0.94 GAA (0.55) LNPEPRAB9AGAACA2ERAP2
SCHEMBL11907457 0.88 LNPEP (0.67) LNPEPRAB9AGAACA2TYMS
SCHEMBL11926971 0.87 LNPEP (0.58) LNPEPRAB9AGAACA2TYMS
SCHEMBL11926048 0.87 GAA (0.51) LNPEPRAB9AGAATAS1R3TAS1R1
SCHEMBL11921833 0.85 GAA (0.52) LNPEPRAB9AGAACA2ERAP2
SCHEMBL7511247 0.83 LNPEP (0.76) LNPEPRAB9AGAACA2TYMS
SCHEMBL7511243 0.83 LNPEP (0.76) LNPEPRAB9AGAACA2TYMS
SCHEMBL11906254 0.82 GAA (0.47) LNPEPRAB9AGAACA2TSHR
SCHEMBL3975599 0.82 LNPEP (0.60) LNPEPRAB9AGAACA2TYMS
SCHEMBL3975596 0.82 LNPEP (0.60) LNPEPRAB9AGAACA2TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 LNPEP 568/4885RAB9A 3255/4885GAA 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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