Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | VDR | P11473 | 3/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22038744 | 0.86 | BRD9 (0.35) | BRD9BRD7ERN1NR1H4THRB | |
| SCHEMBL22038774 | 0.81 | SLC22A12 (0.43) | SLC22A12FFAR1VDRPPARDESR1 | |
| SCHEMBL22038743 | 0.80 | ERN1 (0.34) | BRD9BRD7ERN1 | |
| SCHEMBL22038772 | 0.79 | FFAR1 (0.39) | SLC22A12FFAR1 | |
| SCHEMBL22037244 | 0.78 | HSD17B2 (0.39) | SLC22A12FFAR1VDRPPARD | |
| SCHEMBL20845127 | 0.77 | CRHR1 (0.30) | — | |
| SCHEMBL22037628 | 0.77 | SLC22A12 (0.38) | SLC22A12FFAR1PPARDPPARG | |
| SCHEMBL22037245 | 0.77 | PIK3CD (0.33) | SLC22A12BRD9BRD7 | |
| SCHEMBL22037673 | 0.76 | FFAR1 (0.38) | SLC22A12FFAR1 | |
| SCHEMBL21317993 | 0.76 | PARP15 (0.41) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |