Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037247 | 0.86 | SLC22A12 (0.36) | BRD9BRD7ERN1NR1H4THRB | |
| SCHEMBL22038166 | 0.80 | CHRNA7 (0.36) | SMN1; SMN2RORCTHRB | |
| SCHEMBL22037665 | 0.80 | BRD9 (0.35) | BRD9BRD7ERN1 | |
| SCHEMBL22038181 | 0.78 | PTGER1 (0.38) | SMN1; SMN2HPGDTSHRALDH1A1THRB | |
| SCHEMBL16206079 | 0.75 | BRD9 (0.41) | BRD9BRD7ERN1PRKAG1PRKAA1 | |
| SCHEMBL18831746 | 0.75 | SLC22A12 (0.37) | SMN1; SMN2HPGDRAB9AMAPTGPBAR1 | |
| SCHEMBL20845127 | 0.75 | CRHR1 (0.30) | — | |
| SCHEMBL20686857 | 0.74 | MRGPRX4 (0.47) | SMN1; SMN2HPGDMAPK1RAB9AMAPT | |
| SCHEMBL20195396 | 0.72 | SMN1; SMN2 (0.38) | NR1H4SMN1; SMN2MAPK1MAPT | |
| SCHEMBL23506215 | 0.72 | MRGPRX4 (0.37) | NR1H4HPGDALDH1A1HTTSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |