Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506246 | 0.87 | KDM4E (0.44) | KDM4EGPR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL16144477 | 0.79 | KDM4E (0.42) | KDM4EGPR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL12526215 | 0.79 | GPR3 (0.42) | KDM4EGPR3TSHRHPGDCCNE2 | |
| SCHEMBL22016872 | 0.78 | KDM4E (0.39) | KDM4EGPR3HPGDCCNE2CCNE1 | |
| SCHEMBL22031394 | 0.76 | KDM4E (0.37) | KDM4EGPR3HPGDCCNE2CCNE1 | |
| SCHEMBL21954998 | 0.75 | KDM4E (0.42) | KDM4EGPR3HPGDCYP11B1CYP11B2 | |
| SCHEMBL4105404 | 0.75 | KDM4E (0.42) | KDM4EGPR3CYP3A4TSHRHPGD | |
| SCHEMBL10220777 | 0.75 | KDM4E (0.42) | KDM4EGPR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL30901296 | 0.75 | KDM4E (0.42) | KDM4EGPR3HPGDCYP11B1CYP11B2 | |
| SCHEMBL30901299 | 0.75 | KDM4E (0.42) | KDM4EGPR3CYP3A4TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174256-B2 | Imidazopyridine derivatives | GILEAD SCIENCES, INC. (US) | 2021-11-16 | — | — | US | disclosed |
| US-20200165248-A1 | IMIDAZOPYRIDINE DERIVATIVES | GILEAD SCIENCES, INC. | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174256-B2 | Imidazopyridine derivatives | TPMT, IRAK4, CFTR | KDM4E 2655/4885GPR3 3778/4885CYP3A4 48/4885 |
| US-20200165248-A1 | IMIDAZOPYRIDINE DERIVATIVES | TPMT, IRAK4, CFTR | KDM4E 2655/4885GPR3 3778/4885CYP3A4 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.