Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611267 | 1.00 | KDM4E (0.42) | KDM4EGPR3BACE1F12PLAU | |
| SCHEMBL20989876 | 0.81 | KDM4E (0.42) | KDM4EGPR3BACE1F12PLAU | |
| SCHEMBL12490356 | 0.80 | KDM4E (0.41) | KDM4EGPR3BACE1F12PLAU | |
| SCHEMBL12490232 | 0.79 | KDM4E (0.40) | KDM4EGPR3BACE1F12PLAU | |
| SCHEMBL21954998 | 0.78 | KDM4E (0.42) | KDM4EGPR3BACE1ALDH1A1HPGD | |
| SCHEMBL12526215 | 0.78 | GPR3 (0.42) | KDM4EGPR3BACE1ALDH1A1HPGD | |
| SCHEMBL4105404 | 0.78 | KDM4E (0.42) | KDM4EGPR3ALDH1A1CYP3A4HPGD | |
| SCHEMBL30901296 | 0.78 | KDM4E (0.42) | KDM4EGPR3BACE1ALDH1A1HPGD | |
| SCHEMBL22037342 | 0.75 | KDM4E (0.40) | KDM4EGPR3CYP3A4HPGDTSHR | |
| SCHEMBL28301397 | 0.74 | KDM4E (0.50) | KDM4EGPR3BACE1F12PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462635-A | Quinoline derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-112969687-B | Quinoline derivatives as a4 b 7 integrin inhibitors | 吉利德科学公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-112969700-B | Imidazopyridine derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-112996786-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |