SCHEMBL22037685

SCHEMBL22037685

CC1(C)c2cccc(-c3nc(-c4ccc(-c5ccncc5)cc4)nc(-c4cccc(-c5ccccc5)c4)n3)c2-c2ccc3ccccc3c21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.37
LMNA P02545 6/20 0.37
KDM4E B2RXH2 5/20 0.37
MAPK1 P28482 4/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
PDK2 Q15119 1/20 0.36
TSHR P16473 3/20 0.34
MEN1 O00255 2/20 0.34
USP2 O75604 2/20 0.34
KMT2A Q03164 2/20 0.34
TNF P01375 1/20 0.34
MAPK14 Q16539 2/20 0.34
MAPK11 Q15759 1/20 0.34
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22037511 0.96 MAPT (0.40) MAPTLMNAKDM4EMAPK1ALDH1A1
SCHEMBL22038503 0.96 MAPT (0.40) MAPTLMNAKDM4EMAPK1ALDH1A1
SCHEMBL22038469 0.95 SMN1; SMN2 (0.35) MAPTLMNAKDM4EMAPK1ALDH1A1
SCHEMBL23743372 0.94 TSHR (0.36) MAPTLMNAKDM4EMAPK1ALDH1A1
SCHEMBL22037620 0.92 MAPT (0.40) MAPTLMNAKDM4EMAPK1ALDH1A1
SCHEMBL22037916 0.91 CYP11B1 (0.40) MAPTKDM4EALDH1A1HPGDRAB9A
SCHEMBL23743379 0.91 AURKA (0.35) MAPTKDM4EMAPK1ALDH1A1HPGD
SCHEMBL23743289 0.90 MAPT (0.38) MAPTLMNAKDM4EMAPK1ALDH1A1
SCHEMBL24778314 0.89 ALDH1A1 (0.35) MAPTKDM4EMAPK1ALDH1A1HPGD
SCHEMBL23743298 0.89 ALDH1A1 (0.35) MAPTKDM4EMAPK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200168805-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOOSAN CORPORATION (KR) 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200168805-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ELOVL1, ELOVL6, ELOVL5 MAPT 883/4885LMNA 1161/4885KDM4E 2116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.