SCHEMBL22040145 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	1/20	0.35

▸	LMNA	P02545	2/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	ALPL	P05186	1/20	0.33

▸	HSP90AA1	P07900	1/20	0.33

▸	ALPI	P09923	1/20	0.33

▸	GAA	P10253	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	ALPG	P10696	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	TLR9	Q9NR96	1/20	0.33

▸	L3MBTL1	Q9Y468	1/20	0.33

▸	CMA1	P23946	1/20	0.33

▸	AHR	P35869	1/20	0.33

▸	PKM	P14618	1/20	0.32

▸	TDP2	O95551	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23891650	0.83	CYP3A4 (0.35)	—
SCHEMBL23891578	0.83	CYP3A4 (0.35)	—
SCHEMBL17605645	0.77	KDM1A (0.42)	BACE1CMA1AHRTDP2
SCHEMBL17604798	0.77	KDM1A (0.42)	BACE1CMA1AHRTDP2
SCHEMBL17604801	0.77	KDM1A (0.42)	BACE1CMA1AHRTDP2
SCHEMBL17604740	0.75	TDP2 (0.39)	CMA1AHRTDP2
SCHEMBL17605831	0.75	TDP2 (0.39)	CMA1AHRTDP2
SCHEMBL17604739	0.75	TDP2 (0.39)	CMA1AHRTDP2
SCHEMBL11353054	0.73	AKR1B10 (0.39)	MAPT
SCHEMBL17606651	0.73	LMNA (0.37)	LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020108500-A1	HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF	成都海创药业有限公司	2020-06-04	—	—	WO	disclosed