SCHEMBL220412

SCHEMBL220412

NNC(=O)CN(CC(=O)NN)CC(=O)NN

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
CTSD P07339 1/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
LMNA P02545 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.37
CYP1A2 P05177 1/20 0.37
NFKB1 P19838 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
THPO P40225 1/20 0.37
MAPT P10636 1/20 0.33
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GAA P10253 1/20 0.31
KDM6B O15054 1/20 0.31
KDM4A O75164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219297 0.88 TDP1 (0.46) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL19841396 0.87 CTSD (0.41) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL3359467 0.84 CTSD (0.48) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL23587946 0.80 CTSD (0.35) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL15499795 0.80 TDP1 (0.64) KDM4EKDM5CPHF8KDM2ALMNA
SCHEMBL11384926 0.80 CTSD (0.50) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL20323274 0.80 KDM4E (0.39) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL15131284 0.79 KDM4E (0.42) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL11850983 0.78 MEN1 (0.47) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL154159 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911948-B1 SOIL ANALYSIS METHODS PREC PLANTING LLC (US) 2025-03-26 EP claimed
CN-115722276-A Granular multi-effect adsorbent composition and preparation method thereof 江苏美亚科泽过滤技术有限公司 2023-03-03 CN claimed
US-20160024319-A1 FILM-FORMING COMPOSITION INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE SAINT-GOBAIN ADFORS (FR) 2016-01-28 US claimed
EP-2379465-B1 PAINTER'S CANVAS INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE AND MANUFACTURING PROCESS SAINT GOBAIN ADFORS (FR) 2013-01-02 EP claimed
US-20120245267-A1 FILM-FORMING COMPOSITION INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE SAINT-GOBAIN ADFORS (FR) 2012-09-27 US claimed
US-20120132851-A1 MAT OF MINERAL FIBERS INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE AND MANUFACTURING PROCESSES SAINT-GOBAIN ADFORS (FR) 2012-05-31 US claimed
US-6706818-B2 ONE-PACK TYPE WATER-BASED PAINTS WHICH READILY CURES REGARDLESS OF ENVIRONMENT KANSAI PAINT CO., LTD. (JP) 2004-03-16 US claimed
US-20030139496-A1 Curable resin composition KANSAI PAINT CO., LTD. (JP) 2003-07-24 US claimed
US-20030125471-A1 Curable resin composition KANSAI PAINT CO., LTD. (JP) 2003-07-03 US claimed
US-6559231-B2 Copolymer of an unsaturated monomer having a maleimide group; compound having at least 2 hydrazide, semicarbazide or hydrazone groups KANSAI PAINT CO., LTD. (JP) 2003-05-06 US claimed
EP-1300429-A1 Curable resin composition KANSAI PAINT CO., LTD. (JP) 2003-04-09 EP claimed
US-20030065068-A1 Copolymer of ethylenically unsaturated maleimide group and carbonyl group monomers and a compound having hydrazide, semicarbazide or hydrazone groups KANSAI PAINT CO., LTD. (JP) 2003-04-03 US claimed
EP-1298152-A1 Curable resin composition KANSAI PAINT CO., LTD. (JP) 2003-04-02 EP claimed
EP-1262495-A1 Curable resin composition KANSAI PAINT CO., LTD. (JP) 2002-12-04 EP claimed
US-20020128379-A1 Curing type water base resin composition KANSAI PAINT CO., LTD. (JP) 2002-09-12 US claimed
EP-1211293-A2 Curing type water base resin composition KANSAI PAINT CO., LTD. (JP) 2002-06-05 EP claimed
US-12600909-B2 Etching solution composition RASA INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
US-12590214-B2 Ink-jet ink NIPPON SHOKUBAI CO., LTD. (JP) 2026-03-31 US disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590214-B2 Ink-jet ink MIF, ELANE, SEM1 KDM4E 554/4885CTSD 4651/4885KDM5C 1455/4885
US-12600909-B2 Etching solution composition ASIC3, GRIN2D, ASIC1 KDM4E 279/4885CTSD 531/4885KDM5C 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.