Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994725 | 0.91 | CES2 (0.52) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL3149795 | 0.77 | ESR1 (0.46) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL6255440 | 0.77 | ESR1 (0.46) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL2768215 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL11486502 | 0.76 | ALDH1A1 (0.50) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL12646044 | 0.75 | CES2 (0.60) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL18175062 | 0.75 | ALDH1A1 (0.48) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| Hydrochloric Acid SCHEMBL7317191 | 0.75 | BLM (0.48) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL19074349 | 0.75 | ACHE (0.65) | PLAUALDH1A1LMNACES2CES1 | |
| Hydrochloric Acid SCHEMBL7317199 | 0.75 | BLM (0.48) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020110126-A1 | AGONISTS OF PPAR-δ | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-06-04 | — | — | WO | disclosed |