SCHEMBL2204192

SCHEMBL2204192

Nc1c(Cl)c(Cl)c(N)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21104563 0.91 CA1 (0.32) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL3341501 0.91 CA1 (0.32) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL6449656 0.91 CA1 (0.32) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL7869956 0.87 CA1 (0.36) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL38652792 0.87 CA1 (0.31) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL4705260 0.84 ALDH1A1 (0.33) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL29674828 0.84 ALDH1A1 (0.33) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL7023599 0.80 CA1 (0.32) ALDH1A1CYP3A4CA1CA2CA4
SCHEMBL10945910 0.80 ALDH1A1 (0.37) ALDH1A1GAA
SCHEMBL8059878 0.80 CA1 (0.33) ALDH1A1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409998-A Photo-thermal conversion eutectic material containing N, N, N, N-tetramethyl-p-phenylenediamine and preparation method thereof 汕头大学 2021-02-26 CN claimed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-20210394113-A1 POLYMER AND METHOD FOR PRODUCING THE SAME, GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER, AND m-PHENYLENEDIAMINE COMPOUND FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
CN-110291132-B Copolymerized polyether polyol, polyurethane, and method for producing copolymerized polyether polyol 株式会社可乐丽 2021-12-14 CN disclosed
US-10974207-B2 Gas separation membrane, gas separation membrane module, and gas separation device FUJIFILM CORPORATION (JP) 2021-04-13 US disclosed
US-10654005-B2 Method for producing gas separation composite membrane, liquid composition, gas separation composite membrane, gas separation module, gas separation apparatus, and gas separation method FUJIFILM CORPORATION (JP) 2020-05-19 US disclosed
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-20190176081-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed
US-20190091635-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-4164580-A 4H-s-Triazolo[4,3-a][1,5]benzodiazepin-5-ones as tranquilizers E. R. SQUIBB & SONS, INC. (US) 1979-08-14 US disclosed
US-4133809-A DEPRESSANTS, TRANQUILIZERS, SEDATIVES, GROWTH PROMOTERS, ANTICONVULSANTS, MUSCLE RELAXANTS E. R. SQUIBB & SONS, INC. (US) 1979-01-09 US disclosed
US-4081439-A Aromatic disazo pigments CIBA-GEIGY CORPORATION (US) 1978-03-28 US disclosed
US-4070353-A FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4065449-A Tetrachloro substituted disazo pigments CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4064110-A FROM 5-ALKOXYMETHYL-1,3,4-DIOXAZOL-2-ONES, ALKALI METAL CARBOXYLATE CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-12-20 US disclosed
US-4062838-A LACQUERS, PRINTING INKS, YELLOW TO ORANGE CIBA-GEIGY CORPORATION (US) 1977-12-13 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3956266-A DISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210394113-A1 POLYMER AND METHOD FOR PRODUCING THE SAME, GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER, AND m-PHENYLENEDIAMINE COMPOUND PRMT9, PRMT1, PNMT ALDH1A1 2452/4885CYP3A4 1289/4885CA1 1088/4885
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT ALDH1A1 2452/4885CYP3A4 1289/4885CA1 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.