Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201939 | 0.88 | BCHE (0.35) | BCHEALDH1A1 | |
| SCHEMBL2201883 | 0.77 | RORC (0.32) | RORCSIGMAR1TMEM97MEN1KMT2A | |
| SCHEMBL1636483 | 0.74 | RORC (0.51) | RORCLTB4R2BCHENPC1MEN1 | |
| SCHEMBL2204341 | 0.71 | RORC (0.47) | RORCLTB4R2BCHESIGMAR1TMEM97 | |
| SCHEMBL2201240 | 0.71 | RORC (0.53) | RORC | |
| SCHEMBL2204055 | 0.71 | RORC (0.47) | RORCLTB4R2 | |
| SCHEMBL12509866 | 0.70 | RORC (0.47) | RORCLTB4R2BCHE | |
| SCHEMBL12509950 | 0.69 | RORC (0.46) | RORC | |
| SCHEMBL1638260 | 0.69 | HDAC3 (0.45) | RORCLTB4R2SNCA | |
| SCHEMBL2203028 | 0.69 | RORC (0.53) | RORCLTB4R2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |