Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426460 | 0.79 | BCHE (0.37) | RORCMEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL2201939 | 0.78 | BCHE (0.35) | CA2 | |
| SCHEMBL2201884 | 0.77 | SLC6A9 (0.35) | RORCACHEMEN1KMT2AGRIN1 | |
| SCHEMBL2204339 | 0.77 | RORC (0.43) | RORCMEN1KMT2ATMEM97SIGMAR1 | |
| SCHEMBL12509871 | 0.76 | RORC (0.37) | RORCACHE | |
| SCHEMBL2203825 | 0.74 | TSHR (0.44) | RORCACHECA2 | |
| SCHEMBL4954388 | 0.72 | CA2 (0.38) | RORCACHEKMT2ACA2GRIN1 | |
| SCHEMBL4954391 | 0.72 | CA2 (0.38) | RORCACHEKMT2ACA2GRIN1 | |
| SCHEMBL4951871 | 0.72 | CA2 (0.38) | RORCACHECA2GRIN1GRIN2B | |
| SCHEMBL2200325 | 0.70 | MAOA (0.40) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |