Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201941 | 0.87 | RORC (0.37) | RORCBCHEMEN1KMT2AACHE | |
| SCHEMBL2201884 | 0.76 | SLC6A9 (0.35) | RORCSIGMAR1TMEM97BCHEMEN1 | |
| SCHEMBL2203028 | 0.73 | RORC (0.53) | RORCLTB4R2BCHEACHE | |
| SCHEMBL2201240 | 0.72 | RORC (0.53) | RORC | |
| SCHEMBL2204339 | 0.71 | RORC (0.43) | RORCLTB4R2SIGMAR1TMEM97SNCA | |
| SCHEMBL2200590 | 0.71 | RORC (0.34) | RORCKMT2A | |
| SCHEMBL1636483 | 0.71 | RORC (0.51) | RORCLTB4R2BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2202811 | 0.70 | KMT2A (0.34) | RORCKMT2A | |
| SCHEMBL2203823 | 0.70 | BCHE (0.38) | RORCBCHEACHE | |
| SCHEMBL2203829 | 0.70 | BCHE (0.38) | RORCBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |