Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | UTRN | P46939 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043468 | 0.89 | MAPT (0.69) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL22043484 | 0.83 | MAPT (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL16939846 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL15569860 | 0.78 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL3948187 | 0.78 | UTRN (0.77) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL3948179 | 0.78 | UTRN (0.77) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL2244578 | 0.76 | NPC1 (0.80) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL2242920 | 0.76 | SMN1; SMN2 (0.80) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL2246316 | 0.75 | ALDH1A1 (0.87) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL13254484 | 0.75 | MAPT (0.78) | SMN1; SMN2ALDH1A1POLBKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112605-A1 | COMPOUNDS AND METHODS FOR TREATING CHRONIC MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2020-06-04 | — | — | WO | disclosed |