Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | UTRN | P46939 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043476 | 0.89 | SMN1; SMN2 (0.58) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL22043484 | 0.86 | MAPT (0.56) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL2245387 | 0.82 | RAB9A (0.77) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL16939873 | 0.81 | MAPT (0.73) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL2244509 | 0.81 | MAPT (0.79) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL16939846 | 0.80 | SMN1; SMN2 (0.66) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL6665555 | 0.79 | KMT2A (0.65) | MAPTRAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30452307 | 0.79 | KMT2A (0.65) | MAPTRAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14096592 | 0.79 | MAPT (1.00) | MAPTPOLBRAB9AALDH1A1NPC1 | |
| SCHEMBL2247470 | 0.78 | MAPT (0.89) | MAPTPOLBRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112605-A1 | COMPOUNDS AND METHODS FOR TREATING CHRONIC MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2020-06-04 | — | — | WO | disclosed |