Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 7/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476811 | 0.84 | ROCK1 (0.58) | ROCK2PRKACAGSK3BCLK4KMT2A | |
| SCHEMBL22044466 | 0.84 | MLYCD (0.49) | ROCK2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL13887911 | 0.81 | CYP3A4 (0.61) | ROCK2CDK2GSK3BIRAK4DYRK1A | |
| SCHEMBL22044887 | 0.79 | ROCK2 (0.46) | ROCK2CDC7MAP4K4CLK4PDPK1 | |
| SCHEMBL13887925 | 0.77 | MAPK1 (0.54) | MEN1KMT2AGAALMNA | |
| SCHEMBL22044051 | 0.76 | MLYCD (0.51) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL22044497 | 0.75 | MLYCD (0.48) | ROCK2MLYCDMEN1KMT2APLA2G1B | |
| SCHEMBL22044904 | 0.74 | DYRK1A (0.51) | ROCK2CDC7MAP4K4GSK3BCLK4 | |
| SCHEMBL22044102 | 0.74 | DDR1 (0.48) | ROCK2MLYCDMEN1KMT2APLA2G1B | |
| SCHEMBL22044851 | 0.73 | MEN1 (0.52) | ROCK2CDC7MAP4K4PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786304-A1 | METHOD FOR ADJUSTING RAS UBIQUITINATION | Xiamen University (CN) | 2021-03-03 | — | — | EP | disclosed |
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | Amcure Biosciences Pte. Ltd. (SG) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | KRAS, NRAS, RASSF5 | ROCK2 1660/4885CDC7 786/4885MAP4K4 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.