Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 15/20 | 0.48 |
| ▸ | DDR2 | Q16832 | 11/20 | 0.48 |
| ▸ | KIT | P10721 | 9/20 | 0.48 |
| ▸ | ABL1 | P00519 | 8/20 | 0.48 |
| ▸ | BCR | P11274 | 8/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044486 | 0.85 | DDR1 (0.48) | DDR1DDR2KITABL1BCR | |
| SCHEMBL22044497 | 0.83 | MLYCD (0.48) | ABL1BCRMLYCDMEN1PLA2G1B | |
| SCHEMBL22044156 | 0.81 | DDR1 (0.41) | DDR1DDR2KITABL1BCR | |
| SCHEMBL22044907 | 0.79 | ROCK2 (0.45) | DDR1DDR2KITABL1BCR | |
| SCHEMBL22044466 | 0.74 | MLYCD (0.49) | DDR2MLYCDMEN1PLA2G1BCYP1A2 | |
| SCHEMBL22043993 | 0.74 | ROCK2 (0.54) | MLYCDMEN1PLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL5210610 | 0.72 | MLYCD (0.64) | MLYCDMEN1PLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL1568282 | 0.71 | MLYCD (0.74) | MLYCDMEN1PLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL22044051 | 0.70 | MLYCD (0.51) | DDR2MLYCDMEN1PLA2G1BCYP1A2 | |
| SCHEMBL22044874 | 0.70 | ABL1 (0.43) | ABL1BCRKMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | Amcure Biosciences Pte. Ltd. (SG) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | KRAS, NRAS, RASSF5 | DDR1 3947/4885DDR2 4221/4885KIT 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.