SCHEMBL22044987

SCHEMBL22044987

Cc1cccc(N2c3cccc(C)c3Oc3c2ccc(C)c3C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.41
MGLL Q99685 1/20 0.41
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MAPT P10636 3/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX12 P18054 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 3/20 0.33
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CASP6 P55212 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADRB1 P08588 1/20 0.33
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21692985 0.81 CACNA1B (0.43) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1
SCHEMBL24858829 0.76 MGLL (0.37) MGLLCACNA1BAPBA1L3MBTL1MAPT
SCHEMBL22044194 0.74 HSP90AA1 (0.41) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1
SCHEMBL22044818 0.74 ALDH1A1 (0.35) HSP90AA1MGLLCACNA1BAPBA1MAPT
SCHEMBL15316124 0.70 HSP90AA1 (0.49) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1
SCHEMBL16945821 0.70 HSP90AA1 (0.49) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1
SCHEMBL20789095 0.69 HSP90AA1 (0.55) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1
SCHEMBL22045039 0.68 HSP90AA1 (0.46) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1
SCHEMBL19844326 0.68 P2RX4 (0.37) MGLLCACNA1BAPBA1MAPTALDH1A1
SCHEMBL20788948 0.66 HSP90AA1 (0.52) HSP90AA1MGLLCACNA1BAPBA1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10669473-B2 Organic molecules for use in optoelectronic components CYNORA GMBH (DE) 2020-06-02 US disclosed